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Pregnancy outcome in women with gestational diabetes – A longitudinal study of changes in demography and treatment modalities

Published 22 January 2020 In an increasing but changing population of gestational diabetes women in our region, with more hereditary and non‐Scandinavian origins, but with fewer smokers, metabolic control has improved with maintained favorable pregnancy outcomes, with more frequent use of metformin and substantially less use of insulin treatment. New publication in Obstetrics & Gynaecology

https://www.lupop.lu.se/article/pregnancy-outcome-women-gestational-diabetes-longitudinal-study-changes-demography-and-treatment - 2025-02-04

Cardiorespiratory fitness and long‐term risk of sleep apnea: A national cohort study

Published 22 January 2020 Sleep apnea is increasing in prevalence, and is an important cause of cardiometabolic diseases and mortality worldwide. Its only established modifiable risk factor is obesity; however, up to half of all sleep apnea cases may occur in non‐obese persons, and hence there is a pressing need to identify other modifiable risk factors to facilitate more effective prevention. We

https://www.lupop.lu.se/article/cardiorespiratory-fitness-and-long-term-risk-sleep-apnea-national-cohort-study - 2025-02-04

Smokeless tobacco, snus, at admission for percutaneous coronary intervention and future risk for cardiac events

Published 23 January 2020 Snus use at admission for a first PCI was not associated with a higher occurrence of all-cause mortality, new revascularisation or heart failure hospitalisation. Discontinuing snus after a first PCI was associated with a significantly longer duration to a subsequent PCI. New publication in Interventional cardiology

https://www.lupop.lu.se/article/smokeless-tobacco-snus-admission-percutaneous-coronary-intervention-and-future-risk-cardiac-events - 2025-02-04

The General Population’s View on Where to Seek Treatment for Gambling Disorder – a General Population Survey

Published 23 January 2020 More remains to be understood about attitudes towards treatment for gambling disorder and where to seek treatment. Given the low degree of treatment seeking behaviour in this condition, it may be of interest to study people’s perception about where to seek help in case of problem gambling. From a study originally aiming to address health correlates of problem gambling, th

https://www.lupop.lu.se/article/general-populations-view-where-seek-treatment-gambling-disorder-general-population-survey - 2025-02-04

Neighborhood Deprivation and Risks of Autoimmune Disorders: A National Cohort Study in Sweden

Published 24 January 2020 No study to date, as far as we know, has analyzed the potential effect of neighborhood-level deprivation on autoimmune disorders (ADs), when adjusted for individual-level characteristics. Methods: A total of 5.4 million individuals from 8363 neighborhoods, comprising the whole Swedish population (ages 25–74 years), were followed for the period 1 January 2000, until admiss

https://www.lupop.lu.se/article/neighborhood-deprivation-and-risks-autoimmune-disorders-national-cohort-study-sweden - 2025-02-04

Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer: a population-based cohort study in Skåne, Sweden.

Published 24 January 2020 An increasing number of women are evaluated for potential breast cancer and may experience mental distress during evaluation. We aim to assess the risks of psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer. New publication in Breast Cancer Research

https://www.lupop.lu.se/article/psychiatric-disorders-and-cardiovascular-diseases-during-diagnostic-workup-potential-breast-cancer - 2025-02-04

In sickness or in health? Register-based evidence on partners' mutual receipt of sickness allowance and disability pension

Published 25 January 2020 Studies on partners' mutual receipt of benefits constitute a growing research field in the way individual health and health-related decisions depend on social relations. This paper provides the first study on the mutual receipt of sickness allowance. We analysed married and cohabiting couples' receipt of sickness allowance and disability pension by estimating discrete-tim

https://www.lupop.lu.se/article/sickness-or-health-register-based-evidence-partners-mutual-receipt-sickness-allowance-and-disability - 2025-02-04

Registry-Based Medical Research: Data Dredging or Value Building to Quality of Care?

Published 25 September 2019 Registry-based medical research is an important tool in assessing health care interventions in the general population. Observational studies are used to establish effectiveness whereas randomized clinical trials assess efficacy in an experimental manner targeting a carefully selected population of patients. Medical registries may be office or hospital based, state/provi

https://www.lupop.lu.se/article/registry-based-medical-research-data-dredging-or-value-building-quality-care - 2025-02-04

Data verification of nationwide clinical quality registries

Published 26 September 2019 Clinical auditing is an emerging instrument for quality assessment and improvement.Moreover, clinical registries facilitate medical research as they provide ‘real world’ data. It is importantthat entered data are robust and reliable. The aim of this study was to describe the evolving procedureand results of data verication within the Dutch Institute for Clinical Auditi

https://www.lupop.lu.se/article/data-verification-nationwide-clinical-quality-registries - 2025-02-04

Risk and outcome of hepatocellular carcinoma in liver cirrhosis in Southern Sweden: a population-based study

Published 27 September 2019 Liver cirrhosis is a risk factor for hepatocellular carcinoma (HCC). While the HCC risk is thought to be highest in hepatitis B and hepatitis C, the risk in other cirrhosis etiologies is not fully established. Therefore, we aimed to study the risk and outcome of HCC in alcoholic cirrhosis compared to cirrhosis of other etiologies, in Sweden. New publication in Scandinav

https://www.lupop.lu.se/article/risk-and-outcome-hepatocellular-carcinoma-liver-cirrhosis-southern-sweden-population-based-study - 2025-02-04

Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

Published 30 September 2019 Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor–outcome association. However, the relative importance of selection bias for Mendelian randomization compared with other potential biases is unclear. New publication in International Journa

https://www.lupop.lu.se/article/contextualizing-selection-bias-mendelian-randomization-how-bad-it-likely-be - 2025-02-04

Barriers and Opportunities for Use of Patient Registries in Medicines Regulation

Published 2 October 2019 The European Medicines Agency (EMA) established the Patient Registry Initiative to explore ways of supporting the use of patient registries in generating high-quality data for regulatory decision making and to enable a systematic approach to their use. We review barriers and opportunities for using patient registries in medicines regulation. A key aspect is that early disc

https://www.lupop.lu.se/article/barriers-and-opportunities-use-patient-registries-medicines-regulation - 2025-02-04

Bayesian Methods for Exposure Misclassification Adjustment in a Mediation Analysis

Published 3 October 2019 Soil-transmitted helminth infections have been found to be associated with child development. The objective was to investigate hemoglobin levels and malnutrition as mediators of the association between Ascaris infection and intelligence quotient (IQ) scores in children. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/bayesian-methods-exposure-misclassification-adjustment-mediation-analysis - 2025-02-04

The what, when and how of orthopaedic registers: an introduction into register-based research

Published 4 October 2019 Establishment of orthopaedic registers started in 1975 and many registers have been initiated since. The main purpose of registers is to collect information on patients, implants and procedures in order to monitor and improve the outcome of the specific procedure. New publicatoin in Efort.Read more here

https://www.lupop.lu.se/article/what-when-and-how-orthopaedic-registers-introduction-register-based-research-0 - 2025-02-04